Add to ORKGThe aim of this work was to develop prolonged diltiazem hydrochloride release matrices based on alginate-gelatin mixtures and establish the drug release mechanism. The erosion, swelling, and dissolution behavior of the tablets in different medium were evaluated. The different polyelectrolyte behavior and gel strength between type A Gelatin and type B Gelatin would explain the different swelling, erosion and dissolution behavior in the media with sudden pH change. The similar dissolution behavior in the pH, which simulates the physiological pH through the gastrointestinal tract, should be explained because the same main species for gelatin A and Gelatin B would be present in this media.This work was partially funded by FONDECYT gra...
The evaluation of the effects of different media ionic strengths and pH on the release of hydrochlor...
Purpose: To develop a oral controlled matrix drug delivery system for a highly water soluble drug, d...
Purpose: To develop a oral controlled matrix drug delivery system for a highly water soluble drug, d...
The aim of this work was to develop prolonged diltiazem hydrochloride release matrices based on algi...
The dissolution profiles of formulations based on mixtures of chitosan/alginate depend on the pH. It...
The evaluation of the effects of different media ionic strengths and pH on the release of hydrochlor...
The aim of this work was to investigate the factors influencing the dissolution characteristics of d...
The aim of this work was to establish the diltiazem hydrochloride release mechanism from the chitosa...
The aim of this work was to establish the diltiazem hydrochloride release mechanism from the chitosa...
The aim of this work was to establish the diltiazem hydrochloride release mechanism from the chitosa...
Alginate vehicles are capable of forming a gel matrix in situ when they come into contact with gastr...
Alginate vehicles are capable of forming gel matrix in situ, when comes into contact with gastric me...
This research investigated the use of sodium alginate for the preparation of hydrophylic matrix tabl...
The swelling and dissolution behavior of pharmaceutical systems containing a drug and a polymer can ...
Abstract. Alginate matrix tablet of diltiazem hydrochloride (DTZ), a water-soluble drug, was prepare...
The evaluation of the effects of different media ionic strengths and pH on the release of hydrochlor...
Purpose: To develop a oral controlled matrix drug delivery system for a highly water soluble drug, d...
Purpose: To develop a oral controlled matrix drug delivery system for a highly water soluble drug, d...
The aim of this work was to develop prolonged diltiazem hydrochloride release matrices based on algi...
The dissolution profiles of formulations based on mixtures of chitosan/alginate depend on the pH. It...
The evaluation of the effects of different media ionic strengths and pH on the release of hydrochlor...
The aim of this work was to investigate the factors influencing the dissolution characteristics of d...
The aim of this work was to establish the diltiazem hydrochloride release mechanism from the chitosa...
The aim of this work was to establish the diltiazem hydrochloride release mechanism from the chitosa...
The aim of this work was to establish the diltiazem hydrochloride release mechanism from the chitosa...
Alginate vehicles are capable of forming a gel matrix in situ when they come into contact with gastr...
Alginate vehicles are capable of forming gel matrix in situ, when comes into contact with gastric me...
This research investigated the use of sodium alginate for the preparation of hydrophylic matrix tabl...
The swelling and dissolution behavior of pharmaceutical systems containing a drug and a polymer can ...
Abstract. Alginate matrix tablet of diltiazem hydrochloride (DTZ), a water-soluble drug, was prepare...
The evaluation of the effects of different media ionic strengths and pH on the release of hydrochlor...
Purpose: To develop a oral controlled matrix drug delivery system for a highly water soluble drug, d...
Purpose: To develop a oral controlled matrix drug delivery system for a highly water soluble drug, d...